Yearly Archives: 2022


Neurons derived from the cells of a person with fragile X syndrome develop atypically when transplanted into a mouse’s brain, a new study has found. Some of the differences replicate those seen in the brains of people with fragile X syndrome. Researchers have struggled to create mice that accurately model the condition, […]

Fragile X neurons develop atypically in chimeric mice


[Peter Hess | Spectrum News | September 14, 2022] A large mutation that leads to fragile X syndrome in people does not set off the same genetic cascade in mice, a new study shows. The work highlights the limitations of using mice to model the condition and the need to explore other model animals, […]

Largest-yet fragile X mutation in mice confirms model’s shortcomings


A commonly used screening test creates a gender gap that may hinder diagnosis and treatment for women and girls. [Anne Trafton | MIT News Office | September 8, 2022] In recent years, researchers who study autism have made an effort to include more women and girls in their studies. However, despite these […]

Studies of autism tend to exclude women, researchers find


Using organoids to model early development, researchers used an emerging microscopy technology to see that new neurons struggled to reach their developmental destination. [David Orenstein | Picower Institute for Learning and Memory | August 3, 2022] Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT […]

Advanced imaging reveals mired migration of neurons in Rett syndrome ...



To ensure a quick halt, brain circuit architecture avoids a slow process of integration in favor of quicker differentiation, study finds. [David Orenstein | Picower Institute for Learning and Memory | July 28, 2022] Your new apartment is just a couple of blocks down the street from the bus stop, but today […]

Sprint then stop? The brain is wired for the math ...


Studying speakers of 45 languages, neuroscientists found similar patterns of brain activation and language selectivity. [Anne Trafton | MIT News Office | July 18, 2022] Over several decades, neuroscientists have created a well-defined map of the brain’s “language network,” or the regions of the brain that are specialized for processing language. Found […]

Whether speaking Turkish or Norwegian, the brain’s language network looks ...


[Leah Campbell | Department of Brain and Cognitive Sciences | June 21, 2022] A team of cognitive scientists and doctors finds that patients with aphasia use different cognitive tools to compensate for language deficits. Bruce Willis’s recent announcement that he was retiring from acting brought widespread public attention to the neurological condition […]

Study illuminates trade-off between complex words and complex sentences


[Anne Trafton | MIT News | June 1, 2022] Unexpected outcomes trigger release of noradrenaline, which helps the brain focus its attention and learn from the event. When your brain needs you to pay attention to something important, one way it can do that is to send out a burst of noradrenaline, […]

How the brain responds to surprising events



Source: [Anne Trafton | MIT News Office, May 25, 2022] Modeling study suggests that the muffled environment in utero primes the brain’s ability to interpret some types of sound. Inside the womb, fetuses can begin to hear some sounds around 20 weeks of gestation. However, the input they are exposed to is […]

Early sound exposure in the womb shapes the auditory system


Source: [Jason Sparapani | Department of Materials Science and Engineering | MIT News | May 13, 2022] Professor Polina Anikeeva’s innovation in the treatment of neurological disorders highlights the interdisciplinary nature of her field. A pivotal moment in Polina Anikeeva’s career was when she looked at an MRI scan of Parkinson’s disease […]

Is it neuroscience? Chemistry? Art? Wulff Lecture shows versatility, diversity ...


Source: [David Orenstein | Picower Institute for Learning and Memory | May 2, 2022] Innovative brain-wide mapping study shows that an “engram,” the ensemble of neurons encoding a memory, is widely distributed and includes regions not previously realized. A new study by scientists at The Picower Institute for Learning and Memory at […]

A single memory is stored across many connected brain regions


Source: [MIT News Office | April 28, 2022] Prestigious honor society announces more than 250 new members. Seven MIT faculty members are among more than 250 leaders from academia, the arts, industry, public policy, and research elected to the American Academy of Arts and Sciences, the academy announced Thursday. One […]

Seven from MIT elected to American Academy of Arts and ...



Source: [David Orenstein | Picower Institute for Learning and Memory | April 28, 2022] Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS. Neurodegenerative diseases are defined by an increasingly widespread and debilitating death of nervous system cells, but they also share other […]

Aging Brain Initiative awards fund five new ideas to study, ...


Source: [McGovern News | Jennifer Michalowski | April 26, 2022] From search engines to voice assistants, computers are getting better at understanding what we mean. That’s thanks to language processing programs that make sense of a staggering number of words, without ever being told explicitly what those words mean. Such programs infer […]

What words can convey


With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function Source: [David Orenstein | Picower Institute | April 21, 2022] In a new brain-wide circuit tracing study, scientists at MIT’s Picower Institute for Learning and Memory focused selective attention […]

Circuit that focuses attention brings in wide array of inputs


When artificial intelligence is tasked with visually identifying objects and faces, it assigns specific components of its network to face recognition — just like the human brain. Source: [Jennifer Michalowski | McGovern Institute for Brain Research | April 6, 2022] The human brain seems to care a lot about faces. It’s dedicated […]

An optimized solution for face recognition



These cells, located in the brain’s striatum, appear to help with decision-making that requires evaluating risks and benefits. Source: [Anne Trafton | MIT News Office | March 24, 2022] When we make complex decisions, we have to take many factors into account. Some choices have a high payoff but carry potential risks; […]

Study finds neurons that encode the outcomes of actions


Tracing connections between neuron populations could help researchers map brain circuits that underlie behavior and perception. Source: [Anne Trafton | MIT News Office | March 3, 2022] Using a novel probe for functional magnetic resonance imaging (fMRI), MIT biological engineers have devised a way to monitor individual populations of neurons and reveal […]

New MRI probe can reveal more of the brain’s inner ...


Source: [Picower News, David Orenstein | February 28, 2022] National Institute recognizes innovations and research elucidating neuronal plasticity and computations The American Institute for Medical and Biological Engineering (AIMBE) has elected Mriganka Sur, Newton Professor of Neuroscience in the Department of Brain and Cognitive Sciences at MIT to its College of Fellows. Peers […]

Mriganka Sur elected to the 2022 class of the AIMBE ...


Professor and cognitive neuroscientist recognized for groundbreaking work on the functional organization of the human brain. Source: [Julie Pryor | McGovern Institute for Brain Research | January 31, 2022] The National Academy of Sciences (NAS) has announced that Nancy Kanwisher, the Walter A. Rosenblith Professor of Cognitive Neuroscience in MIT’s Department of Brain and Cognitive […]

Nancy Kanwisher wins National Academy of Sciences Award in the ...



Sharing food and kissing are among the signals babies use to interpret their social world, according to a new study. Source: [Anne Trafton | MIT News Office | January 20, 2022] Learning to navigate social relationships is a skill that is critical for surviving in human societies. For babies and young children, […]

Babies can tell who has close relationships based on one ...