Targeted Projects


The Simons Center for the Social Brain supports collaborative, focused projects undertaken by multiple laboratories to explore in depth specific aspects or types of autism. These Targeted Projects are structured to encourage collaboration among researchers in order to quickly and flexibly address pressing questions in autism research.

Current Projects

Role of the Thalamic Reticular Nucleus in thalamocortical coordination, cognitive processing, and sleep in ASD

Matthew Wilson
Dara Manoach
Guoping Feng

The nature of the pragmatic impairment in autism spectrum disorders

Evelina Fedorenko
Rebecca Saxe
Edward Gibson
Laura Schulz
Joshua Tenenbaum


Previous Projects

Role of the 16p11.2 CNV in autism: genetic, cognitive and synaptic/circuit analyses

Mark Daly
Nancy Kanwisher
Mark Bear
Mriganka Sur

Multi-level analysis of the Shank3 mutation in autism: translating genetic studies into pathophysiological mechanisms and therapeutic targets

Guoping Feng
J. Troy Littleton
Rudolf Jaenisch